Whether airway mucosal acidification drives early progressive lung disease is controversial ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• August 2018

Early life lower respiratory tract illness impairs lung function at 1 year, independent of baseline lung function ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• January 2017

There is growing evidence that lung function in early-life predicts later lung function. Adverse events over the lifespan might influence an individual’s lung function trajectory, resulting in poor respiratory health. The aim of this study is to identify early-life risk factors and their impact on lung function trajectories to prevent long-term lung impairments. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• March 2022

Lung function testing and lung imaging are commonly used techniques to monitor respiratory diseases, such as cystic fibrosis (CF). The nitrogen (N2) multiple-breath washout technique (MBW) has been shown to detect ventilation inhomogeneity in CF, but the underlying pathophysiological processes that are altered are often unclear. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• Jun 2023

Arsenic is the only environmental toxin that has been linked to both malignant and nonmalignant respiratory disease following ingestion, rather than inhalation, making arsenic a unique toxicant to the respiratory system. Chronic exposure to arsenic has been associated with the development of respiratory symptoms, impaired lung function, and chronic lung disease. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• January 2023

Children’s interstitial and diffuse lung disease (chILD) is a complex heterogeneous group of lung disorders. Gene panel approaches have a reported diagnostic yield of ~ 12%. No data currently exist using trio exome sequencing as the standard diagnostic modality. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• September 2022

Kathryn Ramsey KR BSc (Hons), PhD Co-Head, Children's Lung Health kathryn.ramsey@telethonkids.org.au Co-Head, Children's Lung Health Associate Professor Kathryn Ramsey is a National Health and Medical Research Council (NHMRC) Emerging Leader (EL2) ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• November 2022

In this cohort, as compared with the AREST CF cohort, the authors highlight the limited correlation between infection and inflammation with lung function and structural impairment, and that this was mainly explained by the mild changes identified in lung function and on chest CT scan. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• December 2020

In utero exposure to arsenic via drinking water increases the risk of lower respiratory tract infections during infancy and mortality from bronchiectasis in... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• February 2013

To examine the distribution of early structural lung changes in clinically stable infants and young children with cystic fibrosis using chest computed... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• July 2013

Research is needed to determine best practice for genomic testing in the context of child interstitial or diffuse lung disease. We explored parent's and child's health-related quality of life, parents' perceived understanding of a genomic testing study, satisfaction with information and the study and decisional regret to undertake genomic testing. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• February 2022

This paper is about lung disease in patients with cyctic Fibrosis and prevention strategies to slow the onset of lung disease. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• June 2014